Dr. Cao is the chairman, professor, and PhD supervisor at Department of Epidemiology, Second Military Medical University (Shanghai, China). He was the principal scientist of the national key basic research program (973 program), the National Outstanding Youth Scholar, the professor for a special post of “Chang-Jiang scholar award scheme”, and the leading scientist in Oncology especially in liver cancer. Currently, Dr. Cao serves as the editor-in-chief of international journal <hepatoma research>. Dr. Cao was graduated from Second Military Medical University and got his PhD degree, master degree and bachelor degree of clinical medicine, respectively. After graduated, Dr. Cao received his 3.5-year post-doctoral trainings in Baylor College of Medicine and UT MD Anderson cancer center in Texas, USA. The major research interests are to elucidate the mechanisms by which cancers develop and metastasize, identify novel diagnostic, predictive, and prognostic biomarkers, as well as therapeutic targets for some malignancies. Dr. Cao is in charge of the national research projects including the key project, integrated project, key international collaborative project, and COVID-19 specific project from the national natural scientific foundation of China (NSFC). As the first or corresponding author, Dr. Cao published 158 papers in professional English journals. Of those, 34 papers were published in the journals with impact factors of greater than 10. For the first time, Dr. Cao originated a theory of Cancer Evo-Dev, based on his research on hepatitis B virus (HBV)-induced hepatocarcinogenesis and malignancies of other histotypes like colorectal carcinoma, renal cell carcinoma, and gastric cancer. Served as the editor-in-chief, Dr. Cao published 10 books including < Cancer Evo-Dev>. As the first winner, Dr. Cao got the National Natural Science Award, second degree in 2019, the Natural Science Award of the first degree, Department of Education, China, in 2018, the Science and Technology Progress Award of the first degree in Shanghai, China, in 2018, the Science and Technology Progress Award of the first degree, PLA in 1999, the Science and Technology Award of the first degree, Shanghai Medical Association in 2010. Moreover, Dr. Cao was also awarded the National Science and Technology Progress Award of the second degree in 2004 and 2011 as well as the National Science and Technology Team Award in 2012. Dr. Cao got a total of 36 Science and Technology Awards of different degree, and 21 approved patents. Dr. Cao wined “Wu Jie-Ping Award of Medical & Pharmacol Innovation” in 2022 and “Shanghai Talent Scholar” in 2023.